June 2012 Briefing - Internal Medicine
Here are what the editors at HealthDay consider to be the most important developments in Internal Medicine for June 2012. This roundup includes the latest research news from journal articles, as well as the FDA approvals and regulatory changes that are the most likely to affect clinical practice.
Myrbetriq Approved for Overactive Bladder
FRIDAY, June 29 (HealthDay News) -- Myrbetriq (mirabegron) has been approved to treat adults with overactive bladder, a condition affecting some 33 million Americans, the U.S. Food and Drug Administration said Thursday in a news release.
overactive bladder (http://www.nlm.nih.gov/medlineplus/urinaryincontinence.html )
Vegetable Consumption Lowers Risk of Acute Pancreatitis
FRIDAY, June 29 (HealthDay News) -- Vegetable consumption significantly reduces the risk of non-gallstone-related acute pancreatitis, according to a study published online June 27 in Gut.
Abstract (http://gut.bmj.com/content/early/2012/06/08/gutjnl-2012-302521.short?g=w_gut_ahead_tab )Full Text (subscription or payment may be required) (http://gut.bmj.com/content/early/2012/06/08/gutjnl-2012-302521.full )
Objective Decrease in Hot Flashes After Acute Exercise
FRIDAY, June 29 (HealthDay News) -- For perimenopausal and postmenopausal women, a bout of moderate-intensity physical activity (PA) is associated with objective and subjective improvements in hot flashes (HFs), but performing more moderate PA than usual correlates with more self-reported HFs for women with lower levels of fitness, according to a study published online June 25 in Menopause.
Abstract (http://journals.lww.com/menopausejournal/Abstract/publishahead/Effects_of_physical_activity_on_vasomotor.98796.aspx )Full Text (subscription or payment may be required) (http://journals.lww.com/pages/login.aspx?ContextUrl=%2fmenopausejournal%2fsecure%2fpages%2fpurchase.aspx%3fan%3d00042192-900000000-98796 )
Heart Problems Seen in Fetal Growth-Restricted Pregnancy
FRIDAY, June 29 (HealthDay News) -- Women with normotensive fetal growth-restricted pregnancies have impaired myocardial relaxation and asymptomatic diastolic dysfunction, according to a study published online June 25 in Hypertension.
Abstract (http://hyper.ahajournals.org/content/early/2012/06/25/HYPERTENSIONAHA.112.194159.abstract )Full Text (subscription or payment may be required) (http://hyper.ahajournals.org/content/early/2012/06/25/HYPERTENSIONAHA.112.194159.full.pdf+html )
New Single Tablet for HIV Is Integrase Inhibitor Based
FRIDAY, June 29 (HealthDay News) -- For treatment-naive patients with HIV-1 infection, the once-daily tablet with HIV integrase strand transfer inhibitor elvitegravir (EVG), co-formulated with the CYP3A4 inhibitor cobicistat (COBI), emtricitabine (FTC), and tenofovir disoproxil fumarate (TDF), also known as EVG/COBI/FTC/TDF, is noninferior to a ritonavir-boosted (RTV) protease inhibitor regimen of atazanavir (ATV)/RTV+FTC/TDF, according to a phase 3 study published online June 29 in The Lancet.
Abstract (http://www.thelancet.com/journals/lancet/article/PIIS0140-6736(12)60918-0/abstract )Full Text (subscription or payment may be required) (http://www.thelancet.com/journals/lancet/article/PIIS0140-6736(12)60918-0/fulltext )Editorial (subscription or payment may be required) (http://www.thelancet.com/journals/lancet/article/PIIS0140-6736(12)61029-0/fulltext )
Apolipoproteins Are Biomarkers for Diabetic Retinopathy
FRIDAY, June 29 (HealthDay News) -- In patients with diabetes, with or without diabetic retinopathy, serum apolipoproteins (apos) are associated with markers of systemic and retinal microvascular dysfunction, according to a study published in the July issue of Diabetes.
Abstract (http://diabetes.diabetesjournals.org/content/61/7/1785.abstract )Full Text (subscription or payment may be required) (http://diabetes.diabetesjournals.org/content/61/7/1785.full )
Multi-Biomarker Test Measures Level of RA Activity
THURSDAY, June 28 (HealthDay News) -- A novel multi-biomarker disease activity (MBDA) test consistently distinguishes patients with rheumatoid arthritis (RA) with different categories of disease activity, according to a study published online June 26 in Arthritis Care & Research.
Abstract (http://onlinelibrary.wiley.com/doi/10.1002/acr.21767/abstract )Full Text (http://onlinelibrary.wiley.com/doi/10.1002/acr.21767/pdf )
Aspirin Use Linked to Reduced Risk of Barrett's Esophagus
THURSDAY, June 28 (HealthDay News) -- Current aspirin users have a significantly reduced risk of being diagnosed with Barrett's esophagus (BE) on first endoscopy compared with nonusers, according to a study published in the July issue of Clinical Gastroenterology and Hepatology.
Abstract (http://www.cghjournal.org/article/S1542-3565(12)00310-2/abstract )Full Text (subscription or payment may be required) ( http://www.cghjournal.org/article/S1542-3565(12)00310-2/fulltext )
Supreme Court Upholds Health Care Reform Law
THURSDAY, June 28 (HealthDay News) -- The U.S. Supreme Court voted June 28 to uphold the constitutionality of the Patient Protection and Affordable Care Act (PPACA), which has been the subject of debate and multiple lawsuits since its 2010 inception.
More Information (http://consumer.healthday.com/Article.asp?AID=665925 )
Omega-3 Supplements Reduce Inflammation in Overweight
THURSDAY, June 28 (HealthDay News) -- For older adults who are healthy but overweight and sedentary, taking omega-3 polyunsaturated fatty acids (PUFAs) can reduce levels of inflammatory markers, according to a study published online May 26 in Brain, Behavior, and Immunity.
Abstract (http://www.sciencedirect.com/science/article/pii/S0889159112001183 )Full Text (subscription or payment may be required) (http://www.sciencedirect.com/science/article/pii/S0889159112001183 )
Exercise Training After Lung Transplant Found Beneficial
THURSDAY, June 28 (HealthDay News) -- A three-month supervised exercise training program improves daily walking time, quadriceps force, six-minute walking distance, physical functioning, and 24-hour ambulatory blood pressure for lung transplant patients who experience an uncomplicated postoperative period, according to research published in the June issue of the American Journal of Transplantation.
Abstract (http://onlinelibrary.wiley.com/doi/10.1111/j.1600-6143.2012.04000.x/abstract )Full Text (http://onlinelibrary.wiley.com/doi/10.1111/j.1600-6143.2012.04000.x/full )
Hyperinsulinemia in Early Adulthood Tied to Later HTN
THURSDAY, June 28 (HealthDay News) -- Young adults with hyperinsulinemia are significantly more likely to have hypertension (HTN) later in life, regardless of sex, ethnicity, or body weight, according to a study published in the July issue of Diabetes Care.
Abstract (http://care.diabetesjournals.org/content/35/7/1532.abstract )Full Text (subscription or payment may be required) (http://care.diabetesjournals.org/content/35/7/1532.full.pdf+html )
One in Five Newly Admitted to Nursing Home Falls During Stay
THURSDAY, June 28 (HealthDay News) -- About 20 percent of patients who are newly admitted to a nursing home sustain a fall during their stay, according to a study published in the May issue of the Journal of the American Geriatrics Society.
Abstract (http://onlinelibrary.wiley.com/doi/10.1111/j.1532-5415.2012.03931.x/abstract )Full Text (subscription or payment may be required) (http://onlinelibrary.wiley.com/doi/10.1111/j.1532-5415.2012.03931.x/full )
FDA Clears First Weight-Loss Pill in 13 Years
THURSDAY, June 28 (HealthDay News) -- The Arena Pharmaceuticals drug Belviq (lorcaserin hydrochloride) has been approved by the U.S. Food and Drug Administration, the first approval of an anti-obesity medication in 13 years.
overweight and obesity (http://www.cdc.gov/obesity/ )
Risk of Rupture Increases With Size of Cerebral Aneurysm
THURSDAY, June 28 (HealthDay News) -- The natural course of unruptured cerebral aneurysms varies according to their size, location, and shape, according to a study published in the June 28 issue of the New England Journal of Medicine.
Full Text (subscription or payment may be required) (http://www.nejm.org/doi/full/10.1056/NEJMoa1113260 )
Linagliptin Noninferior to Glimepiride in Type 2 Diabetes
THURSDAY, June 28 (HealthDay News) -- The dipeptidyl peptidase-4 inhibitor linagliptin is noninferior to the sulphonylurea glimepiride for second-line glycemic control and is associated with significantly less hypoglycemia and fewer cardiovascular events in patients with type 2 diabetes, according to a study published online June 28 in The Lancet.
Abstract (http://www.thelancet.com/journals/lancet/article/PIIS0140-6736(12)60691-6/abstract )Full Text (subscription or payment may be required) (http://www.thelancet.com/journals/lancet/article/PIIS0140-6736(12)60691-6/fulltext )Editorial (subscription or payment may be required) (http://www.thelancet.com/journals/lancet/article/PIIS0140-6736(12)60859-9/fulltext )
Ringer's Acetate Better for Patients With Severe Sepsis
WEDNESDAY, June 27 (HealthDay News) -- Fluid resuscitation with hydroxyethyl starch (HES) 130/0.4 for patients with severe sepsis leads to an increased risk of death at day 90 and an increased likelihood of requiring renal-replacement therapy, compared with Ringer's acetate, according to a study published online June 27 in the New England Journal of Medicine.
Abstract (http://www.nejm.org/doi/full/10.1056/NEJMoa1204242?query=featured_home )Full Text (http://www.nejm.org/doi/full/10.1056/NEJMoa1204242?query=featured_home#t=article )
Early Surgery Ups Outcomes in Infective Endocarditis
WEDNESDAY, June 27 (HealthDay News) -- For patients with infective endocarditis and large vegetations, early surgery reduces death from any cause and embolic events, compared with conventional treatment, according to a study published in the June 28 issue of the New England Journal of Medicine.
Full Text (subscription or payment may be required) (http://www.nejm.org/doi/full/10.1056/NEJMoa1112843?query=featured_home )Editorial (subscription or payment may be required) (http://www.nejm.org/doi/full/10.1056/NEJMe1205453?query=featured_home )
Environmental Risks ID'd for REM Sleep Behavior Disorder
WEDNESDAY, June 27 (HealthDay News) -- Smoking, head injury, pesticide exposure, and farming are potential environmental and lifestyle risk factors for developing idiopathic REM sleep behavior disorder (RBD), according to research published online June 27 in Neurology.
Abstract (http://www.neurology.org/content/early/2012/06/27/WNL.0b013e31825dd383.abstract )Full Text (subscription or payment may be required) (http://www.neurology.org/content/early/2012/06/27/WNL.0b013e31825dd383.full.pdf+html )
Men and Women Appear to Respond Differently to Statins
WEDNESDAY, June 27 (HealthDay News) -- Statin therapy appears to reduce the risk of recurrent cardiovascular events in both men and women, but it may not reduce the risk of stroke or all-cause mortality in women, according to a meta-analysis published in the June 25 issue of the Archives of Internal Medicine.
Abstract (http://archinte.jamanetwork.com/article.aspx?articleid=1195535#Abstract )Full Text (http://archinte.jamanetwork.com/article.aspx?articleid=1195535 )Editorial (http://archinte.jamanetwork.com/article.aspx?articleid=1195515 )
Long-Term Adverse Cardiac Outcomes for Low-Carb Diets
WEDNESDAY, June 27 (HealthDay News) -- Women who follow low carbohydrate-high protein diets have an increased risk of cardiovascular disease, according to a study published online June 26 in BMJ.
Full Text (http://www.bmj.com/content/344/bmj.e4026 )
Oxytocin Levels Linked to Behavior in Williams Syndrome
WEDNESDAY, June 27 (HealthDay News) -- In patients with Williams Syndrome, which is characterized by a deletion of nearly 30 genes and altered social behaviors, levels of the neuropeptide oxytocin are associated with the altered behaviors, according to a study published online June 12 in PLoS One.
Abstract (http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0038513#abstract0 )Full Text (http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0038513 )
Hospice Visit Number Affects Ability to Die at Home
WEDNESDAY, June 27 (HealthDay News) -- Hospice patients with cancer are more likely to be able to die in the setting of their choice if they receive at least one hospice visit per day during the first four days of hospice care, according to research published online June 25 in the Journal of Clinical Oncology.
Abstract (http://jco.ascopubs.org/content/early/2012/06/20/JCO.2011.41.5711.abstract )Full Text (subscription or payment may be required) (http://jco.ascopubs.org/content/early/2012/06/20/JCO.2011.41.5711.full.pdf+html )
Nomogram Developed to Estimate Early Breast Cancer Survival
WEDNESDAY, June 27 (HealthDay News) -- A nomogram has been developed to predict five- and 10-year mastectomy-free survival (MFS) in older women with early breast cancer and estimate the predicted benefit of radiation therapy (RT) following conservative surgery (CS), according to research published online June 25 in the Journal of Clinical Oncology.
Abstract (http://jco.ascopubs.org/content/early/2012/06/20/JCO.2011.41.0076.abstract )Full Text (subscription or payment may be required) (http://jco.ascopubs.org/content/early/2012/06/20/JCO.2011.41.0076.full.pdf+html )Editorial (http://jco.ascopubs.org/content/early/2012/06/20/JCO.2012.42.7245.full.pdf+html )
Specific Solvents May Increase Risk of Parkinson's Disease
WEDNESDAY, June 27 (HealthDay News) -- Exposure to specific solvents is associated with an increased risk of Parkinson's disease, according to a study published in the June issue of the Annals of Neurology.
Abstract (http://onlinelibrary.wiley.com/doi/10.1002/ana.22629/abstract )Full Text (subscription or payment may be required) (http://onlinelibrary.wiley.com/doi/10.1002/ana.22629/full )
Duplicate Payments by Federal Government Increasing
WEDNESDAY, June 27 (HealthDay News) -- The federal government spends a substantial and increasing amount on individuals who are dually enrolled in separate managed care programs (the Veterans Affairs health care system [VA] and Medicare Advantage plan [MA]), according to a study published online June 26 in the Journal of the American Medical Association to coincide with presentation at the Annual Research Meeting of AcademyHealth, held from June 24 to 26 in Orlando, Fla.
Abstract (http://jama.jamanetwork.com/article.aspx?articleid=1197014#Abstract )Full Text (http://jama.jamanetwork.com/article.aspx?articleid=1197014 )More Information (http://academyhealth.org/events/content.cfm?ItemNumber=882&navItemNumber=529 )
J-Shaped Association for Coffee Consumption, Heart Failure
TUESDAY, June 26 (HealthDay News) -- Habitual consumption of moderate quantities of coffee, up to four cups per day, correlates with a moderately decreased risk of heart failure, but higher consumption potentially increases the risk, according to a review published online June 26 in Circulation: Heart Failure.
Abstract (http://circheartfailure.ahajournals.org/content/early/2012/06/26/CIRCHEARTFAILURE.112.967299.abstract )Full Text (subscription or payment may be required) (http://circheartfailure.ahajournals.org/content/early/2012/06/26/CIRCHEARTFAILURE.112.967299.full.pdf+html )
Low-Fat Diet Cuts Energy Output, Signals Weight Regain
TUESDAY, June 26 (HealthDay News) -- For obese and overweight young adults who have lost weight, a low-fat diet results in the greatest decreases in resting and total energy expenditure, which is an unfavorable effect that makes weight regain more likely; and for overweight and obese adults, a stepped-care weight-loss intervention (STEP) is linked to similar weight loss as a standard behavioral weight-loss intervention (SBWI), at a reduced cost per patient, according to two studies published in the June 27 issue of the Journal of the American Medical Association.
Abstract - Ebbling (http://jama.jamanetwork.com/article.aspx?articleid=1199154#Abstract )Full Text (http://jama.jamanetwork.com/article.aspx?articleid=1199154 )Abstract - Jakicic (http://jama.jamanetwork.com/article.aspx?articleid=1199152#Abstract )Full Text (http://jama.jamanetwork.com/article.aspx?articleid=1199152 )Editorial (http://jama.jamanetwork.com/article.aspx?articleid=1199129 )
Warfarin Safe After Ischemic Stroke in tPA-Treated Patients
TUESDAY, June 26 (HealthDay News) -- For patients receiving tissue plasminogen activator (tPA) after ischemic stroke, warfarin has no effect on the risk of symptomatic intracranial hemorrhage (sICH), according to a study published in the June 27 issue of the Journal of the American Medical Association.
Abstract (http://jama.jamanetwork.com/article.aspx?articleid=1199153#Abstract )Full Text (http://jama.jamanetwork.com/article.aspx?articleid=1199153 )Editorial (http://jama.jamanetwork.com/article.aspx?articleid=1199130 )
Limited Radiation Acceptable in Pediatric Hodgkin's Lymphoma
TUESDAY, June 26 (HealthDay News) -- For patients with favorable-risk Hodgkin's lymphoma who achieve a complete early response to chemotherapy with vinblastine, Adriamycin (doxorubicin), methotrexate, and prednisone (VAMP), two-year event-free survival rates are high with limited use of radiotherapy, according to a study published in the June 27 issue of the Journal of the American Medical Association.
Abstract (http://jama.jamanetwork.com/article.aspx?articleid=1199151#Abstract )Full Text (http://jama.jamanetwork.com/article.aspx?articleid=1199151 )Editorial (http://jama.jamanetwork.com/article.aspx?articleid=1199131 )
Patient-Centered Medical Home Rating Tied to Operating Costs
TUESDAY, June 26 (HealthDay News) -- Federally funded community health centers with higher scores on a patient-centered medical home (PCMH) rating have higher operating costs, according to a study published online June 24 in the Journal of the American Medical Association to coincide with presentation at the Annual Research Meeting of AcademyHealth, held from June 24 to 26 in Orlando, Fla.
Abstract (http://jama.jamanetwork.com/article.aspx?articleid=1197012#Abstract )Full Text (http://jama.jamanetwork.com/article.aspx?articleid=1197012 )Editorial (http://archinte.jamanetwork.com/article.aspx?articleid=1203517 )More Information (http://academyhealth.org/events/content.cfm?ItemNumber=882&navItemNumber=529 )
Use of Electronic Records Tied to Fewer Malpractice Claims
TUESDAY, June 26 (HealthDay News) -- Use of electronic health records (EHRs) is associated with fewer medical malpractice claims among physicians from multiple surgical and medical specialties, according to a research letter published online June 25 in the Archives of Internal Medicine.
Full Text (http://archinte.jamanetwork.com/article.aspx?articleid=1203517 )
Copy Number Variations May Be Linked to Alcohol Dependence
TUESDAY, June 26 (HealthDay News) -- Copy number variations (CNVs) on two chromosomes may be associated with alcohol dependence, according to research published online June 15 in Alcoholism: Clinical & Experimental Research.
Abstract (http://onlinelibrary.wiley.com/doi/10.1111/j.1530-0277.2012.01758.x/abstract )Full Text (subscription or payment may be required) (http://onlinelibrary.wiley.com/doi/10.1111/j.1530-0277.2012.01758.x/full )
Olmesartan May Be Linked to Spruelike Enteropathy
TUESDAY, June 26 (HealthDay News) -- Patients treated with olmesartan may develop a severe form of spruelike enteropathy, which improves after suspension of the drug, according to research published online June 25 in the Mayo Clinic Proceedings.
Abstract (http://www.mayoclinicproceedings.org/article/S0025-6196(12)00558-7/abstract )Full Text (http://www.mayoclinicproceedings.org/article/S0025-6196(12)00558-7/fulltext )
New Global Estimate Ups Number of H1N1-Linked Deaths
TUESDAY, June 26 (HealthDay News) -- The estimated number of global respiratory and cardiovascular deaths associated with the 2009 pandemic influenza A H1N1 is higher than the number of laboratory-confirmed deaths, according to a modeling study published online June 26 in The Lancet Infectious Diseases.
Abstract (http://www.thelancet.com/journals/laninf/article/PIIS1473-3099(12)70121-4/abstract )Full Text (subscription or payment may be required) (http://www.thelancet.com/journals/laninf/article/PIIS1473-3099(12)70121-4/fulltext# )Editorial (subscription or payment may be required) (http://www.thelancet.com/journals/laninf/article/PIIS1473-3099(12)70152-4/fulltext )
Sleep Benefit Seen in Almost Half of Patients With Parkinson's
TUESDAY, June 26 (HealthDay News) -- Close to half of patients with Parkinson's disease may experience improved motor functioning upon awakening (sleep benefit), according to a study published online May 24 in the Journal of Parkinson's Disease.
Abstract (http://iospress.metapress.com/content/p28t381537384571/ )Full Text (http://iospress.metapress.com/content/p28t381537384571/fulltext.pdf )
Ozone Exposure Causes Negative Cardiovascular Changes
MONDAY, June 25 (HealthDay News) -- Ozone exposure in healthy young adults causes an increase in vascular markers of inflammation, changes in fibrinolytic markers that could potentially impair fibrinolysis, and changes in autonomic control of heart rate, according to a study published online June 25 in Circulation.
Abstract (http://circ.ahajournals.org/content/early/2012/05/18/CIRCULATIONAHA.112.094359.abstract )Full Text (http://circ.ahajournals.org/content/early/2012/05/18/CIRCULATIONAHA.112.094359.full.pdf+html )
Task Force Recommends Screening All Adults for Obesity
MONDAY, June 25 (HealthDay News) -- Clinicians should screen all adults for obesity; and, there is a small health benefit for initiating behavioral counseling interventions in a primary care setting for adults without cardiovascular disease (CVD) or its risk factors, according to two recommendation statements published online June 26 in the Annals of Internal Medicine.
Full Text 1 (subscription or payment may be required) (http://annals.org/article.aspx?articleid=1200996 )Full Text 2 (subscription or payment may be required) (http://annals.org/article.aspx?articleid=1200998 )
Obese Asthma Patients Have Reduced Treatment Response
MONDAY, June 25 (HealthDay News) -- Compared with lean patients, obese patients with asthma have higher neutrophil counts and a reduced response to corticosteroid treatment, according to a study published online June 12 in Allergy.
Abstract (http://onlinelibrary.wiley.com/doi/10.1111/j.1398-9995.2012.02855.x/abstract )Full Text (subscription or payment may be required) ( http://onlinelibrary.wiley.com/doi/10.1111/j.1398-9995.2012.02855.x/full )
Advanced BRAF V600E Melanoma Responds to Dabrafenib
MONDAY, June 25 (HealthDay News) -- Patients with BRAF V600E-mutated metastatic melanoma treated with dabrafenib, an inhibitor of mutated BRAF, have significantly improved progression-free survival compared to those treated with dacarbazine, according to a study published online June 25 in The Lancet.
Abstract (http://www.thelancet.com/journals/lancet/article/PIIS0140-6736(12)60868-X/abstract )Full Text (subscription or payment may be required) (http://www.thelancet.com/journals/lancet/article/PIIS0140-6736(12)60868-X/fulltext )Editorial (subscription or payment may be required) (http://www.thelancet.com/journals/lancet/article/PIIS0140-6736(12)60993-3/fulltext )
No Therapy for ~20 Percent With Stage IV Solid Tumors
FRIDAY, June 22 (HealthDay News) -- About 20 percent of patients diagnosed with stage IV metastatic solid tumors do not receive anticancer treatment, according to a study published online June 15 in Cancer.
Abstract (http://onlinelibrary.wiley.com/doi/10.1002/cncr.27658/abstract )Full Text (subscription or payment may be required) (http://onlinelibrary.wiley.com/doi/10.1002/cncr.27658/full )
Many Female Sexual Assault Survivors Have Severe Pain
FRIDAY, June 22 (HealthDay News) -- More than 50 percent of women who survive sexual assault experience severe pain, although few receive medication, according to a study published online June 15 in The Journal of Pain.
Abstract (http://www.jpain.org/article/S1526-5900(12)00619-0/abstract )Full Text (subscription or payment may be required) (http://www.jpain.org/article/S1526-5900(12)00619-0/fulltext )
Low Bone Mass for Young Men on Antiretrovirals for HIV
FRIDAY, June 22 (HealthDay News) -- Young men recently diagnosed with HIV infection, treated with antiretroviral therapy (ART), have lower bone mass, according to a study published online May 9 in Clinical Infectious Diseases.
Abstract (http://cid.oxfordjournals.org/content/early/2012/05/04/cid.cis455.abstract )Full Text (subscription or payment may be required) (http://cid.oxfordjournals.org/content/early/2012/05/04/cid.cis455.full.pdf+html )
Similar Outcomes for Robot-Aided, Conventional Nephrectomy
FRIDAY, June 22 (HealthDay News) -- Robot-assisted and conventional laparoscopic partial nephrectomies have similar outcomes and complication rates, according to a study published in the July issue of The Journal of Urology.
Abstract (http://www.jurology.com/article/S0022-5347(12)02969-2/abstract )Full Text (subscription or payment may be required) (http://www.jurology.com/article/S0022-5347(12)02969-2/fulltext )
Telehealth Intervention Linked to Lower Admission Rates
FRIDAY, June 22 (HealthDay News) -- A telehealth intervention is associated with improved emergency admission rates and lower mortality compared with usual care, according to a study published online June 21 in BMJ.
Full Text (http://www.bmj.com/content/344/bmj.e3874 )Editorial (subscription or payment may be required) (http://www.bmj.com/content/344/bmj.e4201 )
Reduced Efficacy for CRC Screenings Done by Non-GI Docs
FRIDAY, June 22 (HealthDay News) -- Having interval colorectal cancer (CRC) colonoscopy screenings performed by nongastroenterologists compared with gastroenterologists (GIs) results in a noticeable reduction in the long-term CRC prevention rate, according to research published online June 15 in Cancer.
Abstract (http://onlinelibrary.wiley.com/doi/10.1002/cncr.27664/abstract )Full Text (subscription or payment may be required) (http://onlinelibrary.wiley.com/doi/10.1002/cncr.27664/full )
Increased Sick Leave Rates for Long-Term Cancer Survivors
FRIDAY, June 22 (HealthDay News) -- Five years after a cancer diagnosis, employed cancer survivors have a higher sick leave rate compared with prior to their diagnosis, according to a study published in the June issue of the Journal of Cancer Survivorship.
Abstract (http://rd.springer.com/article/10.1007/s11764-012-0228-8 )Full Text (subscription or payment may be required) (http://rd.springer.com/article/10.1007/s11764-012-0228-8 )
Risk Factors ID'd for SCA in Heart Defect Repair Survivors
FRIDAY, June 22 (HealthDay News) -- In adult survivors of surgery for congenital heart disease (CHD), severe subaortic ventricular systolic dysfunction is a significant and independent predictor of sudden cardiac arrest (SCA), according to research published in the July 1 issue of The American Journal of Cardiology.
Abstract (http://www.ajconline.org/article/S0002-9149(12)00860-0/abstract )Full Text (subscription or payment may be required) (http://www.ajconline.org/article/S0002-9149(12)00860-0/fulltext )
Drug-Eluting Stents Offer No Advantage for A-Fib Patients
FRIDAY, June 22 (HealthDay News) -- Drug-eluting stents (DESs) do not seem to offer advantages over bare-metal stents (BMSs) for patients with atrial fibrillation (AF) who undergo percutaneous coronary intervention (PCI) with stent implantation, according to research published in the July 1 issue of The American Journal of Cardiology.
Abstract (http://www.ajconline.org/article/S0002-9149(12)00845-4/abstract )Full Text (subscription or payment may be required) (http://www.ajconline.org/article/S0002-9149(12)00845-4/fulltext )
Sleep Apnea Linked to Diabetic Peripheral Neuropathy
THURSDAY, June 21 (HealthDay News) -- Obstructive sleep apnea (OSA) is independently associated with diabetic peripheral neuropathy, even after adjustment for potential confounders, according to a study published online June 21 in the American Journal of Respiratory and Critical Care Medicine.
Abstract (http://ajrccm.atsjournals.org/content/early/2012/06/20/rccm.201112-2135OC.abstract )Full Text (subscription or payment may be required) (http://ajrccm.atsjournals.org/content/early/2012/06/20/rccm.201112-2135OC.full.pdf+html )
Eating Disorder Symptoms Evident in Women Over 50
THURSDAY, June 21 (HealthDay News) -- For women aged 50 years and older there is wide endorsement of weight and shape concerns and of eating disorder symptoms, dieting, and body checking behaviors, according to a study published online June 21 in the International Journal of Eating Disorders.
Abstract (http://onlinelibrary.wiley.com/doi/10.1002/eat.22030/abstract )Full Text (subscription or payment may be required) (http://onlinelibrary.wiley.com/doi/10.1002/eat.22030/full )
Living Alone Linked to Higher Mortality in Older Adults
THURSDAY, June 21 (HealthDay News) -- Older adults who live alone have a higher risk of death; and elderly adults who report loneliness experience increased functional decline and an increased risk of death, according to two studies published online June 18 in the Archives of Internal Medicine.
Abstract - Udell (http://archinte.jamanetwork.com/article.aspx?articleid=1188041#Abstract )Full Text (http://archinte.jamanetwork.com/article.aspx?articleid=1188041 )Abstract - Perissinotto (http://archinte.jamanetwork.com/article.aspx?articleid=1188033#Abstract )Full Text (http://archinte.jamanetwork.com/article.aspx?articleid=1188033 )Editorial (http://archinte.jamanetwork.com/article.aspx?articleid=1188040 )
Genetic Contribution Detected in Responses to Opioids
THURSDAY, June 21 (HealthDay News) -- The responses to opioid drugs, such as nausea, respiratory depression, and drug liking or disliking, have a significant inherited component, according to a study published in the July issue of Anesthesiology.
Abstract (http://journals.lww.com/anesthesiology/Abstract/2012/07000/Aversive_and_Reinforcing_Opioid_Effects__A.12.aspx )Full Text (http://journals.lww.com/anesthesiology/Fulltext/2012/07000/Aversive_and_Reinforcing_Opioid_Effects__A.12.aspx )
Half of Residents Report Working While Sick
THURSDAY, June 21 (HealthDay News) -- About half of residents have worked while sick, with many reporting feeling obligated to colleagues and patients, according to a research letter published online June 18 in the Archives of Internal Medicine.
Full Text (http://archinte.jamanetwork.com/article.aspx?articleid=1188034 )
Laparoscopic Safer Than Open Surgery for Gastric Bypass
THURSDAY, June 21 (HealthDay News) -- Laparoscopic Roux-en-Y gastric bypass (LRYGB) is safer than open Roux-en-Y gastric bypass (ORYGB), even after adjusting for patient-level variables, according to research published in the June issue of the Archives of Surgery.
Abstract (http://archsurg.jamanetwork.com/article.aspx?articleid=1182942#Abstract )Full Text (subscription or payment may be required) (http://archsurg.jamanetwork.com/article.aspx?articleid=1182942 )
Many Psoriasis Patients Undertreated for CV Risk Factors
THURSDAY, June 21 (HealthDay News) -- A large proportion of patients with moderate-to-severe plaque psoriasis are underdiagnosed and undertreated for cardiovascular (CV) risk factors, according to a study published in the July issue of the Journal of the American Academy of Dermatology.
Abstract (http://www.eblue.org/article/S0190-9622(11)00844-9/abstract )Full Text (subscription or payment may be required) (http://www.eblue.org/article/S0190-9622(11)00844-9/fulltext )
Prevalence of ACS-Induced PTSD Is About 12 Percent
THURSDAY, June 21 (HealthDay News) -- For patients with acute coronary syndromes (ACS), such as myocardial infarction or unstable angina, the prevalence of post-traumatic stress disorder (PTSD) is approximately 12 percent, and the presence of ACS-induced PTSD is associated with a doubling of the risk of subsequent ACS events and death, according to a study published online June 20 in PLoS One.
Abstract (http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0038915#abstract0 )Full Text (http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0038915 )
Diabetes Linked to Cognitive Decline in Older Adults
THURSDAY, June 21 (HealthDay News) -- Diabetes mellitus (DM) is associated with worse cognitive function and greater cognitive decline among older adults, according to a study published online June 18 in the Archives of Neurology.
Abstract (http://archneur.jamanetwork.com/article.aspx?articleID=1183076#Abstract )Full Text (subscription or payment may be required) (http://archneur.jamanetwork.com/article.aspx?articleID=1183076 )
Deep Brain Stimulation Aids Motor Function in Parkinson's
THURSDAY, June 21 (HealthDay News) -- The globus pallidus interna (GPi) and subthalamic nucleus (STN) are both viable deep brain stimulation (DBS) targets for the treatment of motor symptoms in patients with Parkinson's disease, providing stable improvements over 36 months, according to a study published online June 20 in Neurology.
Abstract (http://www.neurology.org/content/early/2012/06/20/WNL.0b013e31825dcdc1.abstract )Full Text (subscription or payment may be required) (http://www.neurology.org/content/early/2012/06/20/WNL.0b013e31825dcdc1.full.pdf+html )Editorial (subscription or payment may be required) (http://www.neurology.org/content/early/2012/06/20/WNL.0b013e31825dce96.extract )
Diabetes Linked to Increased Cause-Specific Mortality
WEDNESDAY, June 20 (HealthDay News) -- Diabetes is linked with a significantly increased risk of death from many diseases, including specific cancers, in both men and women, according to a study published online June 14 in Diabetes Care.
Abstract (http://care.diabetesjournals.org/content/early/2012/06/11/dc12-0002.abstract )Full Text (subscription or payment may be required) (http://care.diabetesjournals.org/content/early/2012/06/11/dc12-0002.full.pdf+html )
Prophylactic Midurethral Sling Reduces Urinary Incontinence
WEDNESDAY, June 20 (HealthDay News) -- For women without preoperative stress incontinence, placement of a midurethral sling at the time of vaginal prolapse surgery correlates with reduced rates of urinary incontinence at three and 12 months as well as increased rates of adverse events, according to a study published in the June 21 issue of the New England Journal of Medicine.
Full Text (subscription or payment may be required) (http://www.nejm.org/doi/full/10.1056/NEJMoa1111967 )Editorial (subscription or payment may be required) (http://www.nejm.org/doi/full/10.1056/NEJMe1204042 )
Hepatitis B Screening Before Chemo Deemed Cost-Effective
WEDNESDAY, June 20 (HealthDay News) -- Universal hepatitis B virus (HBV) screening before chemotherapy for lymphoma reduces costs in most settings, according to a study published online June 18 in the Journal of Clinical Oncology.
Abstract (http://jco.ascopubs.org/content/early/2012/06/18/JCO.2011.40.7510.abstract )Full Text (http://jco.ascopubs.org/content/early/2012/06/18/JCO.2011.40.7510.full.pdf+html )
Smoking Increases Risk of Squamous Cell Carcinoma
WEDNESDAY, June 20 (HealthDay News) -- Smoking increases the risk of cutaneous squamous cell carcinoma but is not associated with an increased risk of basal cell carcinoma or nonmelanoma skin cancer, according to a systematic review and meta-analysis published online June 18 in the Archives of Dermatology.
Abstract (http://archderm.jamanetwork.com/article.aspx?articleid=1184491#Abstract )Full Text (http://archderm.jamanetwork.com/article.aspx?articleid=1184491 )Editorial (http://archderm.jamanetwork.com/article.aspx?articleid=1184499 )
Emerging Lipoprotein Markers Slightly Up CVD Risk Detection
TUESDAY, June 19 (HealthDay News) -- The addition of certain apolipoproteins and lipoproteins to cardiovascular disease (CVD) risk scores containing total cholesterol and high-density lipoprotein cholesterol (HDL-C) slightly improves CVD risk prediction, according to a study published in the June 20 issue of the Journal of the American Medical Association.
Abstract (http://jama.jamanetwork.com/article.aspx?articleid=1187927#Abstract )Full Text (http://jama.jamanetwork.com/article.aspx?articleid=1187927 )Editorial (http://jama.jamanetwork.com/article.aspx?articleid=1187908 )
More Untreated Kidney Failure Seen in Older Adults
TUESDAY, June 19 (HealthDay News) -- The rate of untreated kidney failure is considerably higher in older adults than in younger adults, according to a study published in the June 20 issue of the Journal of the American Medical Association.
Abstract (http://jama.jamanetwork.com/article.aspx?articleid=1187929#Abstract )Full Text (http://jama.jamanetwork.com/article.aspx?articleid=1187929 )Editorial (http://jama.jamanetwork.com/article.aspx?articleid=1187910 )
2011 Estimates of 15 Selected Health Measures Issued
TUESDAY, June 19 (HealthDay News) -- The estimates of selected health measures for 2011, based on National Health Interview Survey (NHIS) data, have been released June 19 by the U.S. Centers for Disease Control and Prevention's National Center for Health Statistics (NCHS).
More Information (http://www.cdc.gov/nchs/nhis/released201206.htm )
Danger Ubiquity Rationalization Endorsed by Tanning Bed Users
TUESDAY, June 19 (HealthDay News) -- Despite medical evidence of the potential hazards of tanning beds, current tanning bed users strongly endorse danger ubiquity rationalizations, according to a research letter published in the June issue of the Archives of Dermatology.
Full Text (http://archderm.jamanetwork.com/article.aspx?articleid=1184370 )
Psoriasis Independently Linked to Risk of Type 2 Diabetes
TUESDAY, June 19 (HealthDay News) -- Psoriasis is an independent risk factor for the development of type 2 diabetes mellitus, and this risk increases with increasing severity of psoriasis, according to a study published online June 18 in the Archives of Dermatology.
Abstract (http://archderm.jamanetwork.com/article.aspx?articleid=1184494#Abstract )Full Text (http://archderm.jamanetwork.com/article.aspx?articleid=1184494 )
Graphic Warning Labels in Cigarette Ads Most Effective
TUESDAY, June 19 (HealthDay News) -- For smokers, graphic warning labels in advertisements improve recall of warning and health risks, according to a study published in the July issue of the American Journal of Preventive Medicine.
Abstract (http://www.ajpmonline.org/article/S0749-3797(12)00207-3/abstract )Full Text (http://www.ajpmonline.org/article/S0749-3797(12)00207-3/fulltext )
Fatigue Linked to COPD Severity, Risk of Hospitalization
TUESDAY, June 19 (HealthDay News) -- For patients with chronic obstructive pulmonary disease (COPD), fatigue is significantly associated with disease severity, and predicts the risk of hospitalization, according to a study published online June 14 in the European Respiratory Journal.
Abstract (http://erj.ersjournals.com/content/early/2012/06/14/09031936.00021412.abstract )Full Text (subscription or payment may be required) (http://erj.ersjournals.com/content/early/2012/06/14/09031936.00021412.full.pdf+html )
High Future Coronary Event Risk in Chronic Kidney Disease
TUESDAY, June 19 (HealthDay News) -- Patients with chronic kidney disease (CKD) have higher rates of myocardial infarction (MI) than those with diabetes, according to a study published online June 19 in The Lancet.
Abstract (http://www.thelancet.com/journals/lancet/article/PIIS0140-6736(12)60572-8/abstract )Full Text (subscription or payment may be required) (http://www.thelancet.com/journals/lancet/article/PIIS0140-6736(12)60572-8/fulltext )Editorial (subscription or payment may be required) (http://www.thelancet.com/journals/lancet/article/PIIS0140-6736(12)60772-7/fulltext )
Research Suggests Flavocoxid Causes Acute Liver Injury
TUESDAY, June 19 (HealthDay News) -- Flavocoxid, a proprietary prescription medical food used to treat osteoarthritis, appears to cause acute liver injury within months of initiating use, according to research published in the June 19 issue of the Annals of Internal Medicine.
Full Text (subscription or payment may be required) (http://annals.org/article.aspx?articleid=1183011 )Editorial (subscription or payment may be required) (http://annals.org/article.aspx?articleid=1183012 )
Poor Outcomes for Hospitalized Patients With Alzheimer's
MONDAY, June 18 (HealthDay News) -- Hospitalization of patients with Alzheimer's disease (AD) is associated with increased risks of death and institutionalization, with the risk further increased for hospitalized patients with delirium, according to a study published in the June 19 issue of the Annals of Internal Medicine.
Full Text (subscription or payment may be required) (http://annals.org/article.aspx?articleid=1183010 )
Psychological Distress Increases Cerebrovascular Death Risk
MONDAY, June 18 (HealthDay News) -- Psychological distress, as assessed using the 12-item General Health Questionnaire (GHQ-12), is associated with an increased risk of death due to cerebrovascular disease and ischemic heart disease, according to a study published online June 18 in CMAJ, the journal of the Canadian Medical Association.
Abstract (http://www.cmaj.ca/content/early/2012/06/18/cmaj.111719 )Full Text (http://www.cmaj.ca/content/early/2012/06/18/cmaj.111719.full.pdf+html )
High-Salt Diet Ups Markers of Endothelial Dysfunction
MONDAY, June 18 (HealthDay News) -- A high-sodium diet is associated with markers of endothelial dysfunction (serum uric acid [SUA] and urine albumin excretion [UAE]), and increased sodium intake in those with high levels of biomarkers correlates with an increased risk of hypertension, according to a study published online June 18 in Circulation.
Abstract (http://circ.ahajournals.org/content/early/2012/05/15/CIRCULATIONAHA.112.096115.abstract )Full Text (http://circ.ahajournals.org/content/early/2012/05/15/CIRCULATIONAHA.112.096115.full.pdf+html )
Patient-Rated Elbow Evaluation Most Responsive Instrument
MONDAY, June 18 (HealthDay News) -- The Patient-Rated Elbow Evaluation form (PREE) is the most responsive instrument to identify and quantify elbow joint-specific changes before and after total elbow arthroplasty, according to a study published online June 5 in Arthritis Care & Research.
Abstract (http://onlinelibrary.wiley.com/doi/10.1002/acr.21744/abstract )Full Text (subscription or payment may be required) (http://onlinelibrary.wiley.com/doi/10.1002/acr.21744/pdf )
Coexistent Lumbar Disorders Complicate Hip Arthroplasty
MONDAY, June 18 (HealthDay News) -- Patients undergoing total hip arthroplasty (THA) who have coexistent lumbar spine disorders (LSDs) do not report as much improvement in pain and function after arthroplasty compared with patients without lumbar disorders, according to a study published in the May issue of The Spine Journal.
Abstract (http://www.thespinejournalonline.com/article/S1529-9430(11)01394-5/abstract )Full Text (subscription or payment may be required) ( http://www.thespinejournalonline.com/article/S1529-9430(11)01394-5/fulltext )
Sleep Apnea Severity Linked to Glycated Hemoglobin Levels
MONDAY, June 18 (HealthDay News) -- For adults without diabetes, obstructive sleep apnea (OSA) severity is independently associated with impaired glucose metabolism, as measured by glycated hemoglobin (HbA1c) levels, according to a study published online June 11 in Diabetes Care.
Abstract (http://care.diabetesjournals.org/content/early/2012/06/04/dc11-2538.abstract )Full Text (subscription or payment may be required) (http://care.diabetesjournals.org/content/early/2012/06/04/dc11-2538.full.pdf+html )
Genetic Variants Predict Outcomes After t-PA Treatment
MONDAY, June 18 (HealthDay News) -- Two genetic variants have been identified that are associated with hemorrhagic transformation (HT) and mortality rates after infusion of tissue plasminogen activator (t-PA) in patients with acute ischemic stroke, according to research published online June 9 in the Annals of Neurology.
Abstract (http://onlinelibrary.wiley.com/doi/10.1002/ana.23664/abstract )Full Text (subscription or payment may be required) (http://onlinelibrary.wiley.com/doi/10.1002/ana.23664/pdf )
Patterns of Unprofessional Behavior by Hospitalists ID'd
MONDAY, June 18 (HealthDay News) -- Hospitalist participation in unprofessional behavior is generally low, and is associated with job characteristics, age, and site, according to a systematic review published online May 16 in the Journal of Hospital Medicine.
Abstract (http://onlinelibrary.wiley.com/doi/10.1002/jhm.1946/abstract )Full Text (subscription or payment may be required) (http://onlinelibrary.wiley.com/doi/10.1002/jhm.1946/full )
Review: Vitamin D Plus Calcium Linked to Mortality Reduction
FRIDAY, June 15 (HealthDay News) -- Analyses of data from individual patients and trials indicate that vitamin D supplementation in combination with calcium is linked to a reduction in mortality for elderly adults, but this effect is not seen for vitamin D alone, according to research published online May 17 in the Journal of Clinical Endocrinology & Metabolism.
Abstract (http://jcem.endojournals.org/content/early/2012/05/17/jc.2011-3328.abstract )Full Text (subscription or payment may be required) (http://jcem.endojournals.org/content/early/2012/05/17/jc.2011-3328.full.pdf+html )
Younger Adult Cancer Survivors in Poorer Health Than Peers
FRIDAY, June 15 (HealthDay News) -- Adolescent and young adult (AYA) cancer survivors -- those ages 15 to 29 years at their first diagnosis -- report higher rates of unhealthy behaviors, chronic medical conditions, and less access to health care than respondents who never had cancer, and may be at risk for poor long-term health outcomes, according to a study published online June 11 in Cancer.
Abstract (http://onlinelibrary.wiley.com/doi/10.1002/cncr.27445/abstract )Full Text (subscription or payment may be required) (http://onlinelibrary.wiley.com/doi/10.1002/cncr.27445/full )
Increase in Visceral Fat Noted After Liposuction
FRIDAY, June 15 (HealthDay News) -- Abdominal liposuction reduces subcutaneous abdominal fat but seems to trigger an increase in visceral fat, which can be averted by physical activity, according to a study published online April 26 in the Journal of Clinical Endocrinology & Metabolism.
Abstract (http://jcem.endojournals.org/content/early/2012/04/25/jc.2012-1012.abstract )Full Text (subscription or payment may be required) (http://jcem.endojournals.org/content/early/2012/04/25/jc.2012-1012.full.pdf+html )
Factors ID'd in Healing Failure of Diabetic Foot Ulcers
FRIDAY, June 15 (HealthDay News) -- Patients with diabetes whose foot ulcers fail to heal have increased inflammation and aberrant growth factor levels, according to a study published online June 11 in Diabetes.
Abstract (http://diabetes.diabetesjournals.org/content/early/2012/06/04/db12-0227.abstract )Full Text (subscription or payment may be required) (http://diabetes.diabetesjournals.org/content/early/2012/06/04/db12-0227.full.pdf+html )
Human Perivascular Stem Cells Superior for Bone Formation
FRIDAY, June 15 (HealthDay News) -- A population of stem cells isolated from adipose tissue can differentiate into bone more easily and efficiently than other fat cell populations, according to a study published online June 11 in Stem Cells Translational Medicine.
Abstract (http://stemcellstm.alphamedpress.org/content/early/2012/06/08/sctm.2012-0002.abstract )Full Text (subscription or payment may be required) (http://stemcellstm.alphamedpress.org/content/early/2012/06/08/sctm.2012-0002.full.pdf+html )
Testosterone Therapy Does Not Up Prostate Cancer Incidence
FRIDAY, June 15 (HealthDay News) -- Testosterone replacement therapy (TRT) appears to be safe and does not increase the incidence of prostate cancer, according to a study published online June 6 in The Journal of Sexual Medicine.
Abstract (http://onlinelibrary.wiley.com/doi/10.1111/j.1743-6109.2012.02808.x/abstract )Full Text (subscription or payment may be required) (http://onlinelibrary.wiley.com/doi/10.1111/j.1743-6109.2012.02808.x/full )
Psoriasis Tied to 14 Other Autoimmune Diseases
FRIDAY, June 15 (HealthDay News) -- Patients with psoriasis have significantly higher odds for having at least one of 14 other autoimmune diseases, according to a study published online June 4 in the Journal of the American Academy of Dermatology.
Abstract (http://www.eblue.org/article/S0190-9622(12)00462-8/abstract )Full Text (subscription or payment may be required) (http://www.eblue.org/article/S0190-9622(12)00462-8/fulltext )
Weight Loss Linked to Reduced Cancer Incidence, Mortality
FRIDAY, June 15 (HealthDay News) -- Weight loss, particularly intentional weight loss, is associated with a reduced incidence of cancer and mortality, especially for women and for obesity-related cancers, according to a review published online June 4 in Obesity Reviews.
Abstract (http://onlinelibrary.wiley.com/doi/10.1111/j.1467-789X.2012.01010.x/abstract )Full Text (subscription or payment may be required) (http://onlinelibrary.wiley.com/doi/10.1111/j.1467-789X.2012.01010.x/full )
Simple, Noninvasive Eye Test May Identify Risk for Stroke
FRIDAY, June 15 (HealthDay News) -- An eye test measuring ocular pulse amplitude (OPA) can be performed by ophthalmologists to detect severe carotid artery stenosis (CAS), a known risk factor for stroke, according to a study published in the June issue of Ophthalmology.
Abstract (http://www.ophsource.org/periodicals/ophtha/article/S0161-6420(11)01243-7/abstract )Full Text (subscription or payment may be required) (http://www.ophsource.org/periodicals/ophtha/article/S0161-6420(11)01243-7/fulltext )
Number of Cancer Survivors May Reach ~18 Million by 2022
THURSDAY, June 14 (HealthDay News) -- Based on current trends and treatment patterns, the estimated number of cancer survivors in the United States is likely to increase to nearly 18 million by Jan. 1, 2022, according to a report published online June 14 in CA: A Cancer Journal for Clinicians.
Abstract (http://onlinelibrary.wiley.com/doi/10.3322/caac.21149/abstract )Full Text (http://onlinelibrary.wiley.com/doi/10.3322/caac.21149/full )
Brain Volume Linked to Walking Outcomes in Diabetes
THURSDAY, June 14 (HealthDay News) -- Gray matter volume is associated with walking outcomes, including speed, stride duration variability, and double support time, in individuals with diabetes, with a stronger correlation seen for those with diabetic peripheral neuropathy (DPN), according to a study published online June 4 in Diabetes Care.
Abstract (http://care.diabetesjournals.org/content/early/2012/05/29/dc11-2463.abstract )Full Text (subscription or payment may be required) (http://care.diabetesjournals.org/content/early/2012/05/29/dc11-2463.full.pdf+html )
CDC: Preventive Health Services Underused Before 2010
THURSDAY, June 14 (HealthDay News) -- Prior to 2010, only about half of all U.S. adults received key preventive health services, according to a report published in the June 15 supplement of the U.S. Centers for Disease Control and Prevention's Morbidity & Mortality Weekly Report.
More Information (http://www.cdc.gov/mmwr/preview/ind2012_su.html )
Pre-Op Breast Pain in ~28 Percent of Breast Cancer Patients
THURSDAY, June 14 (HealthDay News) -- More than a quarter of women about to undergo breast cancer surgery experience breast pain, with genetic polymorphisms in inflammatory cytokines correlating with pain, according to a study published in the May issue of The Journal of Pain.
Abstract (http://www.jpain.org/article/S1526-5900(12)00499-3/abstract )Full Text (subscription or payment may be required) (http://www.jpain.org/article/S1526-5900(12)00499-3/fulltext )
Cognitive Benefit of Omega-3s in Older Adults Questioned
THURSDAY, June 14 (HealthDay News) -- Omega-3 long-chain polyunsaturated fatty acids (PUFA) supplementation has no benefit on cognitive function in cognitively healthy older people, according to a review published online June 13 in The Cochrane Library.
Abstract (http://onlinelibrary.wiley.com/doi/10.1002/14651858.CD005379.pub3/abstract )Full Text (subscription or payment may be required) (http://onlinelibrary.wiley.com/doi/10.1002/14651858.CD005379.pub3/full )
Lifestyle Factors for Low-Motile Sperm Concentration Identified
THURSDAY, June 14 (HealthDay News) -- Common lifestyle factors associated with low-motile sperm concentration (MSC) include a history of testicular cancer, being in manual labor or not working, and black ethnicity, while men who wear loose underwear and have had a previous conception are less likely to have low MSC, according to a study published online June 12 in Human Reproduction.
Abstract (http://humrep.oxfordjournals.org/content/early/2012/06/12/humrep.des183.abstract )Full Text (subscription or payment may be required) (http://humrep.oxfordjournals.org/content/early/2012/06/12/humrep.des183.full )
Autologous Recellularization of a Vein Transplant Feasible
THURSDAY, June 14 (HealthDay News) -- A new technique involving recellularization of a deceased donor vein graft with autologous stem cells may be a viable option for patients who require a vein graft, according to a proof-of-concept study published online June 14 in The Lancet.
Abstract (http://www.thelancet.com/journals/lancet/article/PIIS0140-6736(12)60633-3/abstract )Full Text (subscription or payment may be required) (http://www.thelancet.com/journals/lancet/article/PIIS0140-6736(12)60633-3/fulltext )Editorial (subscription or payment may be required) (http://www.thelancet.com/journals/lancet/article/PIIS0140-6736(12)60817-4/fulltext )
Trend Shows Early Menopause Linked to Cerebral Aneurysm
THURSDAY, June 14 (HealthDay News) -- Younger age of menopause is associated with a trend toward an increased likelihood of cerebral aneurysm, according to a study published online June 13 in the Journal of NeuroInterventional Surgery.
Abstract (http://jnis.bmj.com/content/early/2012/05/31/neurintsurg-2012-010364.short?g=w_jnis_ahead_tab )Full Text (subscription or payment may be required) (http://jnis.bmj.com/content/early/2012/05/31/neurintsurg-2012-010364.full )
Female APOE ε4 Carriers Have Preclinical Signs of Alzheimer's
THURSDAY, June 14 (HealthDay News) -- Healthy elderly women carrying the apolipoprotein E type 4 allele (APOE ε4) show changes in the brain's memory network characteristic of Alzheimer's disease, which can be observed before any symptoms appear, according to a study published in the June 13 issue of The Journal of Neuroscience.
Abstract (http://www.jneurosci.org/content/32/24/8254.abstract )Full Text (subscription or payment may be required) (http://www.jneurosci.org/content/32/24/8254.full )
Statins Exhibit Adverse Effect on Energy, Exertional Fatigue
THURSDAY, June 14 (HealthDay News) -- For relatively healthy individuals, particularly women, statin use may be associated with reduced energy and exertional fatigue, according to a research letter published online June 11 in the Archives of Internal Medicine.
Full Text (http://archinte.jamanetwork.com/article.aspx?articleid=1183454 )
Socioeconomic Correlates of Plague ID'd in New Mexico
THURSDAY, June 14 (HealthDay News) -- Changing socioeconomic indicators seem to correlate with temporal changes in the distribution of Yersinia pestis (Y. pestis) cases in New Mexico, according to a study published in the July issue of the U.S. Centers for Disease Control and Prevention's Emerging Infectious Diseases.
Full Text (http://wwwnc.cdc.gov/eid/article/18/7/12-0121_article.htm )
Ethinyl Estradiol Dose, Progestin Type Affect the Pill's Stroke Risk
WEDNESDAY, June 13 (HealthDay News) -- The risk of thrombotic stroke and myocardial infarction is increased for women who take oral contraceptives that include ethinyl estradiol, with the relative risk varying according to the dose of ethinyl estradiol and the progestin type, according to a study published in the June 14 issue of the New England Journal of Medicine.
Full Text (subscription or payment may be required) (http://www.nejm.org/doi/full/10.1056/NEJMoa1111840?query=featured_home )Editorial (subscription or payment may be required) (http://www.nejm.org/doi/full/10.1056/NEJMe1204769?query=featured_home )
Whole-Genome Sequencing Can Identify MRSA Outbreaks
WEDNESDAY, June 13 (HealthDay News) -- High throughput, whole-genome sequencing of methicillin-resistant Staphylococcus aureus (MRSA) isolates can provide important phylogenetic information in a clinically relevant time frame, according to a study published in the June 14 issue of the New England Journal of Medicine.
Full Text (subscription or payment may be required) (http://www.nejm.org/doi/full/10.1056/NEJMoa1109910?query=featured_home )
Fecal Incontinence Costs ~$4,000 Per Patient Annually
WEDNESDAY, June 13 (HealthDay News) -- Direct medical and nonmedical costs, plus indirect costs, including loss of productivity, for the treatment of fecal incontinence average $4,110 per patient annually, according to a study published in the May issue of Diseases of the Colon & Rectum.
Abstract (http://journals.lww.com/dcrjournal/Abstract/2012/05000/Economic_Cost_of_Fecal_Incontinence.13.aspx )Full Text (subscription or payment may be required) (http://journals.lww.com/pages/login.aspx?ContextUrl=%2fdcrjournal%2fsecure%2fpages%2fpurchase.aspx%3fan%3d00003453-201205000-00013 )
Curbing Antibiotic Prophylaxis Doesn't Up Endocarditis Risk
WEDNESDAY, June 13 (HealthDay News) -- The incidence of viridans group streptococci infective endocarditis (VGS-IE) has not increased since the publication of the 2007 American Heart Association (AHA) guidelines restricting prophylactic antibiotics in dental patients, according to a study published online June 11 in Circulation.
Abstract (http://circ.ahajournals.org/content/early/2012/05/31/CIRCULATIONAHA.112.095281.abstract )Full Text (http://circ.ahajournals.org/content/early/2012/05/31/CIRCULATIONAHA.112.095281.full.pdf+html )
Telomeres Longer in Offspring of Older Fathers/Grandfathers
WEDNESDAY, June 13 (HealthDay News) -- Increased paternal and paternal grandfather age at birth is associated with longer telomeres in offspring, according to a study published online June 11 in the Proceedings of the National Academy of Sciences.
Abstract (http://www.pnas.org/content/early/2012/06/05/1202092109 )Full Text (subscription or payment may be required) (http://www.pnas.org/content/early/2012/06/05/1202092109.full.pdf+html )
Poor Oral Hygiene Found Predictive of Cancer Mortality
WEDNESDAY, June 13 (HealthDay News) -- Poor oral hygiene, as determined by an increased amount of dental plaque, is a significant and independent predictor of cancer-related death, according to a study published online June 11 in BMJ Open.
Abstract (http://bmjopen.bmj.com/content/2/3/e001083.short?g=w_open_current_tab )Full Text (http://bmjopen.bmj.com/content/2/3/e001083.full )
Cannabinoid Formulation Benefits Opioid-Refractory Pain
WEDNESDAY, June 13 (HealthDay News) -- A novel cannabinoid formulation, nabiximols, is safe and effective for patients with advanced cancer and opioid-refractory pain, especially at a low-dose, according to a study published in the May issue of The Journal of Pain.
Abstract (http://www.jpain.org/article/S1526-5900(12)00019-3/abstract )Full Text (subscription or payment may be required) (http://www.jpain.org/article/S1526-5900(12)00019-3/fulltext )
Task Force Questions Use of Vitamin D, Calcium Supplements
TUESDAY, June 12 (HealthDay News) -- Current evidence is insufficient to support the use of vitamin D and calcium supplements to protect against cancer or osteoporotic fractures, according to a draft recommendation issued by the U.S. Preventive Services Task Force (USPSTF).
Draft Recommendation Statement (http://www.uspreventiveservicestaskforce.org/draftrec3.htm )
Advanced Imaging, Radiation Exposure Up Over Last Decade
TUESDAY, June 12 (HealthDay News) -- From 1996 to 2010 there was an increase in the use of advanced diagnostic imaging and associated radiation exposure within integrated health care systems, according to a study published in the June 13 issue of the Journal of the American Medical Association.
Abstract (http://jama.jamanetwork.com/article.aspx?articleID=1182858#Abstract )Full Text (http://jama.jamanetwork.com/article.aspx?articleID=1182858 )Editorial (http://jama.jamanetwork.com/article.aspx?articleid=1182842 )
Gender Gap Exists in Physician Researchers' Salaries
TUESDAY, June 12 (HealthDay News) -- A survey of mid-career academic physician researchers shows that gender differences in salary exist even after adjusting for differences in specialty, institutional characteristics, academic productivity, academic rank, and work hours, according to a study published in the June 13 issue of the Journal of the American Medical Association.
Abstract (http://jama.jamanetwork.com/article.aspx?articleID=1182859#Abstract )Full Text (http://jama.jamanetwork.com/article.aspx?articleID=1182859 )
Genital Reconstruction Reduces Pain, Restores Pleasure
TUESDAY, June 12 (HealthDay News) -- Following female genital mutilation, reconstructive surgery is associated with improvements or no worsening in pain, and restoration of pleasure, for most women, according to a study published online June 12 in The Lancet.
Abstract (http://www.thelancet.com/journals/lancet/article/PIIS0140-6736(12)60400-0/abstract )Full Text (subscription or payment may be required) (http://www.thelancet.com/journals/lancet/article/PIIS0140-6736(12)60400-0/fulltext )Editorial (subscription or payment may be required) (http://www.thelancet.com/journals/lancet/article/PIIS0140-6736(12)60636-9/fulltext )
Short-Term Meditation Improves Brain Function
TUESDAY, June 12 (HealthDay News) -- Meditating for only a few weeks leads to improved white matter changes in areas of the brain linked to self-regulation, according to a study published online June 11 in the Proceedings of the National Academy of Sciences.
Abstract (http://www.pnas.org/content/early/2012/06/05/1207817109.abstract )Full Text (subscription or payment may be required) (http://www.pnas.org/content/early/2012/06/05/1207817109.full.pdf+html )
Viscosupplementation Deemed Ineffective for Treating Knee OA
TUESDAY, June 12 (HealthDay News) -- Viscosupplementation for osteoarthritis of the knee results in minimal reduction in pain scores while potentially increasing the risk for flare-ups and serious adverse events, according to research published online June 11 in the Annals of Internal Medicine.
Abstract (http://www.annals.org/content/early/2012/06/05/0003-4819-157-3-201208070-00473?aimhp )Full Text (subscription or payment may be required) (http://www.annals.org/content/early/2012/06/05/0003-4819-157-3-201208070-00473.full )
Hospital Noises Affect Brain Activity, Heart Rate in Patients
TUESDAY, June 12 (HealthDay News) -- Typical hospital noises that frequently disrupt the sleep of hospitalized patients influence both cortical brain activity and increase patient heart rate, potentially having a negative impact on the patient's healing and cardiovascular health, according to research published online June 11 in the Annals of Internal Medicine.
Abstract (http://www.annals.org/content/early/2012/06/05/0003-4819-156-12-201208070-00472?aimhp )Full Text (subscription or payment may be required) (http://www.annals.org/content/early/2012/06/05/0003-4819-156-12-201208070-00472.full )
Walking Speed May Be Early Marker of Cognitive Impairment
MONDAY, June 11 (HealthDay News) -- For elderly patients, walking speed and its variability may help distinguish individuals with mild cognitive impairment (MCI) from those with normal cognition, according to a study published in the June 12 issue of Neurology.
Abstract (http://www.neurology.org/content/78/24/1946.abstract )Full Text (subscription or payment may be required) (http://www.neurology.org/content/78/24/1946.full )
Thiazolidinedione Use Linked to Diabetic Macular Edema
MONDAY, June 11 (HealthDay News) -- Treatment with a thiazolidinedione is associated with an increased one- and 10-year risk of diabetic macular edema (DME) in patients with type 2 diabetes, according to a study published online June 11 in the Archives of Internal Medicine.
Abstract (http://archinte.jamanetwork.com/article.aspx?articleID=1182550#Abstract )Full Text (http://archinte.jamanetwork.com/article.aspx?articleID=1182550 )
Susceptibility Loci Identified for Migraine Without Aura
MONDAY, June 11 (HealthDay News) -- Genome-wide association analysis has identified susceptibility loci for migraine without aura, two of which overlap with previously reported migraine loci, according to a study published online June 10 in Nature Genetics.
Abstract (http://www.nature.com/ng/journal/vaop/ncurrent/abs/ng.2307.html )Full Text (subscription or payment may be required) (http://www.nature.com/ng/journal/vaop/ncurrent/full/ng.2307.html#/access )
Many PCPs Recommend Colorectal Cancer Screening in Elderly
MONDAY, June 11 (HealthDay News) -- A substantial portion of primary care physicians (PCPs) recommend screening elderly patients with advanced cancer for colorectal cancer (CRC), according to a study published online June 1 in the Journal of General Internal Medicine.
Abstract (http://www.springerlink.com/content/qw07kn783848l428/ )Full Text (subscription or payment may be required) (https://springerlink3.metapress.com/content/qw07kn783848l428/resource-secured/?target=fulltext.pdf&sid=nlwlacvl0rhskuj2b2ienic3&sh=www.springerlink.com )
Two Groups of Cells ID'ed in Healing Potential of Omentum
FRIDAY, June 8 (HealthDay News) -- Immunomodulatory myeloid-derived suppressor cells and omnipotent stem cells are two of the groups of cells in the omentum which are involved in tissue repair, according to an experimental study published online June 6 in PLoS One.
Abstract (http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0038368#abstract0 )Full Text (http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0038368 )
Three Percent of Hip, Knee Replacements Need Critical Care
FRIDAY, June 8 (HealthDay News) -- Three percent of patients who undergo knee and hip replacements require critical care services (CCS), and they are more likely to be older and have more comorbidities than those who do not require CCS, according to a study published online May 24 in Anesthesiology.
Abstract (http://journals.lww.com/anesthesiology/Abstract/onlinefirst/Utilization_of_Critical_Care_Services_among.98779.aspx )Full Text (subscription or payment may be required) (http://journals.lww.com/anesthesiology/Abstract/onlinefirst/Utilization_of_Critical_Care_Services_among.98779.aspx )
Prediabetes Linked to Increased Risk of Stroke
FRIDAY, June 8 (HealthDay News) -- Prediabetes may be associated with a higher risk of future stroke if defined as impaired glucose tolerance or a combination of impaired fasting glucose and impaired glucose tolerance, according to a study published online June 7 in BMJ.
Full Text (http://www.bmj.com/content/344/bmj.e3564 )Editorial (subscription or payment may be required) (http://www.bmj.com/content/344/bmj.e3285 )
Higher Risk of VTE in CKD Surgical Patients on Enoxaparin
FRIDAY, June 8 (HealthDay News) -- For patients with chronic kidney disease (CKD) who undergo total hip replacement (THR), the rate of major venous thromboembolism (VTE) is significantly higher in those treated with enoxaparin compared to those treated with desirudin, according to a study published online June 4 in the Journal of Thrombosis and Haemostasis.
Abstract (http://onlinelibrary.wiley.com/doi/10.1111/j.1538-7836.2012.04803.x/abstract )Full Text (subscription or payment may be required) (http://onlinelibrary.wiley.com/doi/10.1111/j.1538-7836.2012.04803.x/pdf )
Prevalence, Predictors of Interval Colorectal Cancer ID'd
FRIDAY, June 8 (HealthDay News) -- A variety of procedural and biologic factors contribute to the development of interval colorectal cancers, seen in 7.2 percent of Medicare beneficiaries, according to a study published in the June 15 issue of Cancer.
Abstract (http://onlinelibrary.wiley.com/doi/10.1002/cncr.26602/abstract )Full Text (subscription or payment may be required) (http://onlinelibrary.wiley.com/doi/10.1002/cncr.26602/full )
Link Between Vascular Disease and Disc Height Loss Examined
FRIDAY, June 8 (HealthDay News) -- The association between vascular disease, as measured by abdominal aortic calcifications (AACs), and disc height loss is independent of cardiovascular disease and is largely explained by patient age, gender, and body mass index (BMI), according to a study published in the April issue of The Spine Journal.
Abstract (http://www.thespinejournalonline.com/article/S1529-9430(12)00274-4/abstract )Full Text (subscription or payment may be required) (http://www.thespinejournalonline.com/article/S1529-9430(12)00274-4/fulltext )
Elimination Diet Can Treat Eosinophilic Esophagitis in Adults
FRIDAY, June 8 (HealthDay News) -- A six-food elimination diet can successfully treat adults with eosinophilic esophagitis (EoE), according to a study published in the June issue of Gastroenterology.
Abstract (http://www.gastrojournal.org/article/S0016-5085(12)00309-5/abstract )Full Text (subscription or payment may be required) (http://www.gastrojournal.org/article/S0016-5085(12)00309-5/fulltext )
Waist Size Independently Linked to Type 2 Diabetes Risk
FRIDAY, June 8 (HealthDay News) -- Waist circumference (WC) is independently associated with the risk of type 2 diabetes, and the association is particularly strong for women, according to a study published online June 5 in PLoS Medicine.
Abstract (http://www.plosmedicine.org/article/info%3Adoi%2F10.1371%2Fjournal.pmed.1001230#abstract1 )Full Text (subscription or payment may be required) (http://www.plosmedicine.org/article/info%3Adoi%2F10.1371%2Fjournal.pmed.1001230 )
Venous Thromboembolism Up in Adult Hospitalizations
THURSDAY, June 7 (HealthDay News) -- Every year, more than half a million hospitalized U.S. adults acquire venous thromboembolism (VTE), a growing public health concern that is often preventable, according to research published in the June 8 issue of the U.S. Centers for Disease Control and Prevention's Morbidity & Mortality Weekly Report.
Full Text (http://www.cdc.gov/mmwr/preview/mmwrhtml/mm6122a1.htm?s_cid=mm6122a1_w )
Rule Combo Accurately Predicts Organ Failure in Pancreatitis
THURSDAY, June 7 (HealthDay News) -- A series of 12 predictive rules that combines existing scoring systems in patients with acute pancreatitis improves the accuracy of predicting persistent organ failure, according to a study published in the June issue of Gastroenterology.
Abstract (http://www.gastrojournal.org/article/S0016-5085(12)00338-1/abstract )Full Text (subscription or payment may be required) (http://www.gastrojournal.org/article/S0016-5085(12)00338-1/fulltext )
NAFLD Independently Linked to Cardiovascular Disease
THURSDAY, June 7 (HealthDay News) -- Nonalcoholic fatty liver disease (NAFLD) is independently associated with an increased risk of cardiovascular disease (CVD), but it is not associated with a statistically significantly increased risk of cardiovascular mortality, according to a study published in the June issue of Clinical Gastroenterology and Hepatology.
Abstract (http://www.cghjournal.org/article/S1542-3565(12)00055-9/abstract )Full Text (subscription or payment may be required) (http://www.cghjournal.org/article/S1542-3565(12)00055-9/fulltext )Editorial (http://www.cghjournal.org/article/S1542-3565(12)00228-5/fulltext )
Elevated Antibody Component Tied to Worse General Survival
THURSDAY, June 7 (HealthDay News) -- Middle-aged and elderly individuals with elevated levels of immunoglobulin free light chains (FLCs), without plasma cell disorders, have a two-fold higher risk of death, according to a study published in the June issue of the Mayo Clinic Proceedings.
Abstract (http://www.mayoclinicproceedings.org/article/S0025-6196(12)00388-6/abstract )Full Text (http://www.mayoclinicproceedings.org/article/S0025-6196(12)00388-6/fulltext )Editorial (http://www.mayoclinicproceedings.org/article/S0025-6196(12)00471-5/fulltext )
Hospital Observation Services Rising for Medicare Enrollees
THURSDAY, June 7 (HealthDay News) -- From 2007 to 2009, there was an increase in the prevalence and duration of hospital observation services for Medicare beneficiaries, according to a study published in the June issue of Health Affairs.
Abstract (http://content.healthaffairs.org/content/31/6/1251.abstract?sid=500ae75b-1d4b-43fd-9167-c3e39c000227 )Full Text (subscription or payment may be required) (http://content.healthaffairs.org/content/31/6/1251.full )
Low Risk of Herpes Zoster Recurrence in Elderly
WEDNESDAY, June 6 (HealthDay News) -- For older immunocompetent adults, the risk of herpes zoster recurrence following a recent initial episode is fairly low in both vaccinated and unvaccinated cohorts, according to a study published online June 4 in the Journal of Infectious Diseases.
Abstract (http://jid.oxfordjournals.org/content/early/2012/05/25/infdis.jis334.abstract )Full Text (subscription or payment may be required) (http://jid.oxfordjournals.org/content/early/2012/05/25/infdis.jis334.full )
Vismodegib Has Antitumor Activity in Basal Cell Carcinoma
WEDNESDAY, June 6 (HealthDay News) -- A small-molecule inhibitor of the hedgehog pathway, vismodegib, is associated with tumor response in patients with metastatic or locally advanced basal cell carcinoma (BCC); and vismodegib is efficacious for preventing and treating BCCs in patients with basal cell nevus syndrome, according to two studies published in the June 7 issue of the New England Journal of Medicine.
Full Text - Sekulic (subscription or payment may be required) (http://www.nejm.org/doi/full/10.1056/NEJMoa1113713 )Full Text - Tang (subscription or payment may be required) (http://www.nejm.org/doi/full/10.1056/NEJMoa1113538 )Editorial (subscription or payment may be required) (http://www.nejm.org/doi/full/10.1056/NEJMe1202170 )
Multidrug-Resistance Seen in ~10 Percent of TB Cases in China
WEDNESDAY, June 6 (HealthDay News) -- About one in 10 patients with tuberculosis in China has multidrug-resistant (MDR) tuberculosis; and a new drug, delamanid, is significantly better than placebo for increasing sputum-culture conversion at two months in patients with MDR tuberculosis, according to two studies published in the June 7 issue of the New England Journal of Medicine.
Full Text - Zhao (subscription or payment may be required) (http://www.nejm.org/doi/full/10.1056/NEJMoa1108789?query=featured_home )Full Text - Gler (subscription or payment may be required) (http://www.nejm.org/doi/full/10.1056/NEJMoa1112433?query=featured_home )Editorial (subscription or payment may be required) (http://www.nejm.org/doi/full/10.1056/NEJMe1204478?query=featured_home )
Endurance Training May Induce Adverse Cardiac Remodeling
WEDNESDAY, June 6 (HealthDay News) -- Excessive endurance training may induce adverse cardiovascular remodeling in some individuals, according to a review published in the June issue of the Mayo Clinic Proceedings.
Abstract (http://www.mayoclinicproceedings.org/article/S0025-6196(12)00473-9/abstract )Full Text (http://www.mayoclinicproceedings.org/article/S0025-6196(12)00473-9/fulltext )
PCI Has Excellent Outcomes for Younger Adults With CAD
WEDNESDAY, June 6 (HealthDay News) -- For younger adults with premature coronary artery disease (CAD), percutaneous coronary intervention (PCI) is associated with excellent short- and long-term outcomes, according to a study published in the June 15 issue of The American Journal of Cardiology.
Abstract (http://www.ajconline.org/article/S0002-9149(12)00686-8/abstract )Full Text (subscription or payment may be required) (http://www.ajconline.org/article/S0002-9149(12)00686-8/fulltext )
Cigarette Tax, Price Increases Reduce Smoking in Pregnancy
WEDNESDAY, June 6 (HealthDay News) -- Tobacco control policies, including taxation and price increases, and smoke-free policies are associated with a reduction in maternal smoking during pregnancy, according to a study published online June 5 in the American Journal of Preventive Medicine.
Full Text (http://www.ajpmonline.org/webfiles/images/journals/amepre/AMEPRE_3422[4]-stamped.pdf )
Anti-HTN Drugs Have Distinct Effect on Central, Brachial SBP
WEDNESDAY, June 6 (HealthDay News) -- A reduction in central to brachial amplification induced by some antihypertensive drugs may result in lesser reductions in central than brachial systolic blood pressure, according to research published online May 25 in the British Journal of Clinical Pharmacology.
Abstract (http://onlinelibrary.wiley.com/doi/10.1111/j.1365-2125.2012.04342.x/abstract )Full Text (subscription or payment may be required) (http://onlinelibrary.wiley.com/doi/10.1111/j.1365-2125.2012.04342.x/pdf )
Many Adults May Accidentally Overdose on Acetaminophen
WEDNESDAY, June 6 (HealthDay News) -- About a quarter of adults may accidentally overdose on over-the-counter (OTC) acetaminophen-containing products, and almost half overdose by "double-dipping" with two acetaminophen-containing products, according to a study published online May 26 in the Journal of General Internal Medicine.
Abstract (http://www.springerlink.com/content/h2w2868k87v01w57/ )Full Text (subscription or payment may be required) (https://springerlink3.metapress.com/content/h2w2868k87v01w57/resource-secured/?target=fulltext.html&sid=wxfqqw4tveiubnt3toeibdt1&sh=www.springerlink.com )
Racial Gap in Life Expectancy Down From 2003 to 2008
WEDNESDAY, June 6 (HealthDay News) -- From 2003 to 2008, the gap in life expectancy between non-Hispanic blacks and whites in the United States decreased by about one year for both men and women, according to a research letter published in the June 6 issue of the Journal of the American Medical Association.
Full Text (http://jama.jamanetwork.com/article.aspx?articleid=1172038 )
Risk of Calcium Oxalate Stones Not Affected by Oxalate Intake
TUESDAY, June 5 (HealthDay News) -- Eating large amounts of oxalate does not significantly affect the risk of developing calcium oxalate stones if the recommended amount of dietary calcium is also eaten, according to a study published in the June issue of Urology.
Abstract (http://www.goldjournal.net/article/S0090-4295(12)00162-8/abstract )Full Text (subscription or payment may be required) (http://www.goldjournal.net/article/S0090-4295(12)00162-8/fulltext )
Telephone Therapy Effective for Treating Depression
TUESDAY, June 5 (HealthDay News) -- Telephone-administered cognitive behavioral therapy (T-CBT) correlates with reduced attrition and similar post-treatment improvement in depression compared to face-to-face CBT, but at six months, those who undergo face-to-face CBT are significantly less depressed, according to a study published in the June 6 issue of the Journal of the American Medical Association.
Abstract (http://jama.jamanetwork.com/article.aspx?articleid=1172045#Abstract )Full Text (http://jama.jamanetwork.com/article.aspx?articleid=1172045 )
Troponin T May Help Predict Death After Noncardiac Surgery
TUESDAY, June 5 (HealthDay News) -- Elevated peak troponin T (TnT) measurements in the first three days after noncardiac surgery are associated with an increased risk of 30-day mortality, according to a study published in the June 6 issue of the Journal of the American Medical Association.
Abstract (http://jama.jamanetwork.com/article.aspx?articleid=1172044#Abstract )Full Text (http://jama.jamanetwork.com/article.aspx?articleid=1172044 )
Aspirin Ups Risk of Bleeding in All But Diabetes Patients
TUESDAY, June 5 (HealthDay News) -- Aspirin use is associated with an increased risk of major bleeding, while patients with diabetes have a high risk of bleeding, independent of aspirin use, according to a study published in the June 6 issue of the Journal of the American Medical Association.
Abstract (http://jama.jamanetwork.com/article.aspx?articleid=1172042#Abstract )Full Text (http://jama.jamanetwork.com/article.aspx?articleid=1172042 )Editorial (http://jama.jamanetwork.com/article.aspx?articleid=1172021 )
Pollution Exposure, Obesity Linked to Poor Asthma Control
TUESDAY, June 5 (HealthDay News) -- Higher exposure to traffic pollutants and obesity increase the likelihood of poor asthma control in older adults, according to a study published in the June issue of the Annals of Allergy, Asthma & Immunology.
Abstract (http://www.annallergy.org/article/S1081-1206(12)00267-0/abstract )Full Text (subscription or payment may be required) (http://www.annallergy.org/article/S1081-1206(12)00267-0/fulltext )
In A-Fib, Rhythm Control Reduces Mortality in Long Term
TUESDAY, June 5 (HealthDay News) -- Elderly patients with atrial fibrillation have reduced mortality over the long term if they initiate rhythm control treatment rather than rate control treatment, according to a study published online June 4 in the Archives of Internal Medicine.
Abstract (http://archinte.jamanetwork.com/article.aspx?articleID=1171906#Abstract )Full Text (http://archinte.jamanetwork.com/article.aspx?articleID=1171906 )Editorial (http://archinte.jamanetwork.com/article.aspx?articleid=1171907 )
Childhood Famine Increases Risk of Type 2 Diabetes
TUESDAY, June 5 (HealthDay News) -- Even a short period of moderate or severe undernutrition or famine during childhood or adolescence can increase the risk of developing type 2 diabetes in adulthood, according to research published online May 29 in Diabetes.
Abstract (http://diabetes.diabetesjournals.org/content/early/2012/05/24/db11-1559.short )Full Text (subscription or payment may be required) (http://diabetes.diabetesjournals.org/content/early/2012/05/24/db11-1559.full.pdf+html )
Many Patients Keep Using PPIs After Negative GERD Test
TUESDAY, June 5 (HealthDay News) -- Nearly half of patients continue to use proton pump inhibitors (PPIs) even after pH studies confirm that they do not have gastroesophageal reflux disease (GERD), and most do not recall being instructed to stop taking PPIs, according to a study published in the June issue of Clinical Gastroenterology and Hepatology.
Abstract (http://www.cghjournal.org/article/S1542-3565(12)00215-7/abstract )Full Text (subscription or payment may be required) (http://www.cghjournal.org/article/S1542-3565(12)00215-7/fulltext )
Basal Cell Carcinoma Response Affected by Past + Recent Stress
MONDAY, June 4 (HealthDay News) -- For patients with basal cell carcinoma (BCC), parental emotional maltreatment combined with a severe life event in the past year correlates with poor immune response to the BCC tumor, according to a study published in the June issue of the Archives of General Psychiatry.
Abstract (http://archpsyc.jamanetwork.com/article.aspx?articleid=1171961#Abstract )Full Text (subscription or payment may be required) (http://archpsyc.jamanetwork.com/article.aspx?articleid=1171961 )
Statewide Coordinated STEMI Approach Deemed Successful
MONDAY, June 4 (HealthDay News) -- A statewide coordinated effort across hospitals and emergency medical service (EMS) providers to transport patients with ST-segment elevation myocardial infarction (STEMI) to hospitals providing percutaneous coronary intervention (PCI) has resulted in improved outcomes, according to a study published online June 4 in Circulation.
Abstract (http://circ.ahajournals.org/content/early/2012/05/31/CIRCULATIONAHA.111.068049.abstract )Full Text (subscription or payment may be required) (http://circ.ahajournals.org/content/early/2012/05/31/CIRCULATIONAHA.111.068049.full.pdf+html )Editorial (subscription or payment may be required) (http://circ.ahajournals.org/content/early/2012/06/01/CIRCULATIONAHA.112.114140.abstract )
Soy-Rich Diet Not Found to Improve Global Cognition
MONDAY, June 4 (HealthDay News) -- Long-term dietary supplementation with isoflavone-rich soy protein does not appear to improve the global cognition of healthy postmenopausal women, according to research published in the June 5 issue of Neurology.
Abstract (http://www.neurology.org/content/78/23/1841.abstract )Full Text (subscription or payment may be required) (http://www.neurology.org/content/78/23/1841.full )
More Fruit, Veggies, Exercise Ups Survival in Older Women
MONDAY, June 4 (HealthDay News) -- Higher fruit and vegetable intake combined with exercise improves survival in older women, according to a study published in the May issue of the Journal of the American Geriatrics Society.
Abstract (http://onlinelibrary.wiley.com/doi/10.1111/j.1532-5415.2012.03924.x/abstract )Full Text (subscription or payment may be required) (http://onlinelibrary.wiley.com/doi/10.1111/j.1532-5415.2012.03924.x/full )
Acute Purine Intake Can Up Risk of Gout Attacks Nearly Five-Fold
MONDAY, June 4 (HealthDay News) -- Patients with gout can be nearly five-fold more likely to have gout attacks if they eat purine-rich foods such as meat, seafood, mushrooms, and spinach, with animal sources posing a greater risk than plant sources, according to a study published online May 30 in the Annals of the Rheumatic Diseases.
Abstract (http://ard.bmj.com/content/early/2012/05/20/annrheumdis-2011-201215.abstract?sid=b5685bfd-86c0-415a-bd04-1583df9fc290 )Full Text (subscription or payment may be required) (http://ard.bmj.com/content/early/2012/05/20/annrheumdis-2011-201215.full )
Metabolic Syndrome Linked to Arterial Stiffness in CKD
MONDAY, June 4 (HealthDay News) -- For patients with chronic kidney disease (CKD), those with metabolic syndrome (MetS) have increased arterial stiffness but no increase in endothelial dysfunction, compared to those without MetS, according to a study published online May 29 in Diabetes Care.
Abstract (http://care.diabetesjournals.org/content/early/2012/05/22/dc11-2345.abstract )Full Text (subscription or payment may be required) (http://care.diabetesjournals.org/content/early/2012/05/22/dc11-2345.full.pdf+html )
Morbid Obesity Ups Complication Rate in Spinal Fusion Surgery
MONDAY, June 4 (HealthDay News) -- Morbid obesity increases the risk of multiple complications in spinal fusion surgery, particularly in patients undergoing anterior cervical or posterior lumbar procedures, according to research published in the May 15 issue of Spine.
Abstract (http://journals.lww.com/spinejournal/Abstract/2012/05150/Morbid_Obesity_Increases_Cost_and_Complication.12.aspx )Full Text (subscription or payment may be required) (http://journals.lww.com/pages/login.aspx?ContextUrl=%2fspinejournal%2fsecure%2fpages%2fpurchase.aspx%3fan%3d00007632-201205150-00012 )
Low-Birth-Weight Teens Report Health Similar to Peers
MONDAY, June 4 (HealthDay News) -- Adolescents born with extremely low birth weight (ELBW) in the 1990s assess their current health and well-being similarly to teens born at normal birth weight but report less risk taking, according to a study published online June 4 in Pediatrics.
Abstract (http://pediatrics.aappublications.org/content/early/2012/05/29/peds.2011-3402.abstract )Full Text (subscription or payment may be required) (http://pediatrics.aappublications.org/content/early/2012/05/29/peds.2011-3402.full.pdf+html )
Gene Variants Impact Smokers' Response to Cessation Therapy
FRIDAY, June 1 (HealthDay News) -- Smokers with certain high-risk genetic variants find it more difficult to quit smoking but are more likely to respond to cessation pharmacotherapy, according to a study published online May 30 in the American Journal of Psychiatry.
Abstract (http://ajp.psychiatryonline.org/Article.aspx?ArticleID=1169679 )Full Text (subscription or payment may be required) (http://ajp.psychiatryonline.org/Article.aspx?ArticleID=1169679 )
Ischemic Stroke Risk Higher in Women With A-Fib
FRIDAY, June 1 (HealthDay News) -- Women with atrial fibrillation have a moderately higher risk of ischemic stroke than men, even after accounting for multiple cofactors for stroke, according to a study published online May 31 in BMJ.
Full Text (http://www.bmj.com/content/344/bmj.e3522 )Editorial (subscription or payment may be required) (http://www.bmj.com/content/344/bmj.e3789 )
Disability in Juvenile Arthritis Affects Adult Employment
FRIDAY, June 1 (HealthDay News) -- Disability resulting from juvenile idiopathic arthritis (JIA) can affect educational attainment and ultimately impact employment in adulthood, according to a study published online May 31 in Arthritis & Rheumatism.
Abstract (http://onlinelibrary.wiley.com/doi/10.1002/art.34499/abstract )Full Text (subscription or payment may be required) (http://onlinelibrary.wiley.com/doi/10.1002/art.34499/pdf )
Rats Regain Ability to Walk After Spinal Cord Injury
FRIDAY, June 1 (HealthDay News) -- Rats with spinal cord injury are able to regain locomotion after electrochemical treatment and encouragement of supraspinally mediated movements, in a cortical-dependent manner, according to a study published in the June 1 issue of Science.
Abstract (http://www.sciencemag.org/content/336/6085/1182.abstract )Full Text (subscription or payment may be required) (http://www.sciencemag.org/content/336/6085/1182.full )
Pioglitazone Use Ups Bladder Cancer Risk in Type 2 Diabetes
FRIDAY, June 1 (HealthDay News) -- For patients with type 2 diabetes, use of the oral hypoglycemic agent pioglitazone correlates with an increased risk of bladder cancer, with the risk increasing with duration of use, according to a study published online May 31 in BMJ.
Full Text (http://www.bmj.com/content/344/bmj.e3645 )Editorial (subscription or payment may be required) (http://www.bmj.com/content/344/bmj.e3500 )
Dark Chocolate May Prevent Cardio Events in High-Risk
FRIDAY, June 1 (HealthDay News) -- For individuals with metabolic syndrome at high risk for cardiovascular events, daily consumption of dark chocolate offers a long-term, cost-effective way of reducing the number of cardiovascular events, according to a study published online May 31 in BMJ.
Full Text (http://www.bmj.com/content/344/bmj.e3657 )
PTSD Linked to Urinary Incontinence in Female Veterans
FRIDAY, June 1 (HealthDay News) -- Posttraumatic stress disorder (PTSD) is independently associated with urgency/mixed urinary incontinence (UI) symptoms in female veterans, according to a study published in the June issue of the American Journal of Obstetrics & Gynecology.
Abstract (http://www.ajog.org/article/S0002-9378(12)00400-0/abstract )Full Text (subscription or payment may be required) (http://www.ajog.org/article/S0002-9378(12)00400-0/fulltext )
Global Cancer Incidence Set to Top 20 Million Per Year by 2030
FRIDAY, June 1 (HealthDay News) -- Assuming current trends continue, the global incidence of all-cancer cases is set to increase to more than 20 million per year by 2030, according to a study published online June 1 in The Lancet Oncology.
Abstract (http://www.thelancet.com/journals/lanonc/article/PIIS1470-2045(12)70211-5/abstract )Full Text (subscription or payment may be required) (http://www.thelancet.com/journals/lanonc/article/PIIS1470-2045(12)70211-5/fulltext )
Skin Testing Not Sufficient to ID Contrast Media Sensitivity
FRIDAY, June 1 (HealthDay News) -- More than 50 percent of patients with nonimmediate reactions to iodinated contrast media (CM) are identified with the drug provocation test (DPT) and not with skin testing, according to a study published online May 15 in Allergy.
Abstract (http://onlinelibrary.wiley.com/doi/10.1111/j.1398-9995.2012.02840.x/abstract )Full Text (subscription or payment may be required) (http://onlinelibrary.wiley.com/doi/10.1111/j.1398-9995.2012.02840.x/full )
Heart Rate Affected by Nocturnal Hypoglycemia in T1DM Patients
FRIDAY, June 1 (HealthDay News) -- For adults with type 1 diabetes there is a marked decrease in the low-frequency component of heart rate variability during spontaneous nocturnal hypoglycemia, according to a study published online May 18 in Diabetes Care.
Abstract (http://care.diabetesjournals.org/content/early/2012/05/17/dc11-2120.abstract )Full Text (subscription or payment may be required) (http://care.diabetesjournals.org/content/early/2012/05/17/dc11-2120.full.pdf+html )
Peer Coaches, Staff Support Beneficial in Uncontrolled HTN
FRIDAY, June 1 (HealthDay News) -- For African-American patients with uncontrolled hypertension, an intervention consisting of peer- and practice-based support is associated with reduced systolic blood pressure (SBP) and a nonsignificant trend toward reduced coronary heart disease (CHD) risk at four years, according to a study published online May 9 in the Journal of General Internal Medicine.
Abstract (http://www.springerlink.com/content/01268713611hk946/ )Full Text (subscription or payment may be required) (https://springerlink3.metapress.com/content/01268713611hk946/resource-secured/?target=fulltext.html&sid=y4xsp0inhwlfze2kwt5aqnck&sh=www.springerlink.com )
Low-Carb Diets Not Harmful to Kidneys of Healthy Obese Patients
FRIDAY, June 1 (HealthDay News) -- Low-carbohydrate diets are safe for otherwise healthy obese individuals and there is no evidence that these diets cause kidney damage, according to a study published online May 31 in the Clinical Journal of the American Society of Nephrology.
Abstract (http://cjasn.asnjournals.org/content/early/2012/05/30/CJN.11741111.abstract )Full Text (subscription or payment may be required) (http://cjasn.asnjournals.org/content/early/2012/05/30/CJN.11741111.full )
